Spectrum of Transfusion Transmitted Infections Among Apparently Healthy Blood Donors in Blood Bank RIMS Ranchi From 2008 to 2014

Sushma Kumari, Ritesh Kumar, Ramesh Kumar Srivastava


Context: Apparently healthy blood donors might carry out transfusion transmitted infections which might be fatal for the donor himself as well as the recipient later on.

Aim: To assess the seroprevalence of transfusion-transmitted infections (TTI) among apparently healthy blood donors in Ranchi, India.

Methods and Materials: All blood samples were screened for HIV-I and II, HBsAg, HCV (by using third generation enzyme-linked immunoadsorbent assay technique), Syphilis (by Rapid Plasma Reagin Kit), and Malaria antigen both for plasmodium  falciparum and plasmodium vivax (by One step, rapid, immunochromatographic test).

Result: On screening of 106,306 blood units for TTIs, 1,462 (1.37 %) donors were found positive for one of the TTIs. Highest prevalence was for HBV (970 donors - 0.91%) ranging from 0.73% to 1.19%. This was followed by Malaria (272 donors - 0.25%) ranging from 0.08% to 0.48%, HCV (127 donors - 0.11%) ranging from 0.04% to 0.25%, HIV (72 donors - 0.06%) ranging from 0.03% to 0.10%, and syphilis (21 donors 0.01%) ranging from 0.00% to 0.09%.

Conclusions: Apparently healthy blood donors are not omitted from the danger of transfusion-transmitted infection.



Transfusion-transmitted infections, Immunodeficiency virus, Hepatitis B, Hepatitis C, Syphilis, Malaria

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